Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs
نویسندگان
چکیده
منابع مشابه
Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs.
The chemical structure of a drug determines its physicochemical properties, further determines its ADME/Tox properties, and ultimately affects its pharmacological activity. Medicinal chemists can regulate the pharmacological activity of drug molecules by modifying their structure. Ring systems and functional groups are important components of a drug. The proportion of non-hydrocarbon atoms amon...
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ژورنال
عنوان ژورنال: Molecules
سال: 2016
ISSN: 1420-3049
DOI: 10.3390/molecules21010075